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[01]

BIOIDENTICAL ESTRADIOL (E2)

For estrogen deficiency support, menopausal symptom relief, & peri-/postmenopausal hormone therapy


Course: Individually prescribed by a healthcare specialist according to clinical needs and treatment goals

Key Ingredients: Micronized Estradiol, USP · 0.17 mg per metered dose · Pentravan ® Cream Base

Clinical Basis:

  • One of the primary natural estrogens in the female body,
  • Binds to estrogen receptors and supports estrogen-dependent signaling,
  • Participates in regulation of the reproductive system,
  • Influences bone tissue health and bone metabolism,
  • Is involved in thermoregulation and vasomotor stability,
  • When systemic therapy is clinically appropriate, may help compensate for insufficient endogenous estradiol.


Pentravan ®  Cream Base is designed to enhance penetration and absorption of active pharmaceutical ingredients through the skin.

Key Effects:

  • Support for estrogen deficiency correction,
  • Support for relief of menopausal vasomotor symptoms, including hot flashes and night sweats,
  • Hormonal support during peri- and postmenopausal periods,
  • Support for estrogen-dependent physiologic functions under medical supervision.

Recommended For:

  • Symptoms of estrogen deficiency,
  • Menopausal vasomotor symptoms, including hot flashes and night sweats,
  • Hormone therapy in confirmed estrogen insufficiency,
  • Other conditions where systemic estradiol therapy is considered medically justified.

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